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The presence of the specialized tripeptide KPV allows researchers to monitor the competitive downregulation of nuclear factor kappa B (NF-kB) and trace the inhibition of pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) within inflamed intestinal or cutaneous tissues
Tao W, Wang N, Ruan J, Cheng X, Fan L, Zhang P, et al
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Larger doses were most effective ( Other studies have observed similar conclusions, though the results are mixed